Molecular Mimicry, Bystander Activation, or Viral Persistence: Infections and Autoimmune Disease

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Molecular mimicry, bystander activation, or viral persistence: infections and autoimmune disease.

Virus infections and autoimmune disease have long been linked. These infections often precede the occurrence of inflammation in the target organ. Several mechanisms often used to explain the association of autoimmunity and virus infection are molecular mimicry, bystander activation (with or without epitope spreading), and viral persistence. These mechanisms have been used separately or in vario...

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ژورنال

عنوان ژورنال: Clinical Microbiology Reviews

سال: 2006

ISSN: 0893-8512,1098-6618

DOI: 10.1128/cmr.19.1.80-94.2006